Localização: Botton-Champalimaud Pancreatic Cancer Center
Entidade Empregadora: Champalimaud Foundation
Posição: Research Técnico de Investigação
Início da Candidatura: 24 Abr. 2026
Offer Description
We are looking for a Laboratory Technician to be part of the Advanced Omics Platforms (AOP) of Botton-Champalimaud Pancreatic Cancer Centre, to provide technical services to support the current operation.
Sample Processing: Process human pancreatic tissues and patient-derived organoids into high-quality single-cell or single-nucleus suspensions using
mechanical and enzymatic dissociation protocols.
Quality Control: Perform rigorous quality control on isolated cells using techniques such as Flow Cytometry/FACS, Trypan Blue staining, and automated or manual cell counters.
Sequencing Preparation: Load single-cell suspensions onto the 10x Genomics Chromium Controller to generate barcoded suspensions ready for library generation and sequencing on the Illumina NextSeq 2000 instrument.
Protocol Execution: Perform laboratory protocols in accordance with Standard Operating Procedures (SOPs) to produce reliable and precise data for scientific research.
Sample Management: Handle fresh and archival samples (fresh-frozen and FFPE) from patient material and perform data entry/tracking using Laboratory Information Management Systems (LIMS).
Maintenance & Compliance: Ensure the cleanliness of the AOP lab space to comply with Quality System Regulation requirements and help maintain laboratory stocks of kits and reagents.
Collaboration: Develop positive relationships with internal teams, resolve technical issues efficiently, and participate in routine lab meetings to contribute to research planning.
STANDARDS OF PERFORMANCE
Proactively looking for opportunities to improve service provision and subsequent delivery on the improvements identified.
All individuals are expected to be flexible in undertaking the duties and responsibilities attached to their job and may be asked to perform other duties which reasonably correspond to the general character of their job and their level of responsibility.
All individuals are expected to maintain personal and professional development to meet the changing demands of the job and participate in appropriate learning and development activities.
Requirements
Research Field: Biological sciences
Education Level: Master Degree or equivalent
Years of Research Experience: 1 - 4
Skills / Qualifications
Essential Qualifications & Experience
Education: PhD or other post-graduate level qualification in life or medical sciences.
Languages: Proficient in both English and Portuguese.
Technical Skills: Significant experience with a variety of cell biology techniques including:
- Expertise in aseptic technique, tissue dissection, and the isolation of high-quality cells and/or nuclei from human tissues that are either fresh frozen or FFPE.
- Proficiency in viability counting and Flow Cytometry/FACS.
- Ability to follow SOPs and experimental workflows accurately and efficiently.
Soft Skills: Strong communication, organizational and IT skills.
Desirable Qualifications
- Single-cell sequencing experiments using the 10x Genomics Chromium Controller using either Flex or EpiMultiome.
- Experience with other 10x Genomics platforms such as the VisiumCytAssist and Xenium.
- Experience with Next-generation library workflows such as ATAC-seq.
- Dataentry and sampletracking using LIMS and document management systems.
Specific Requirements
KEY SKILLS
- Leadership
- Problem solving
- Flexibility
- Attention to Detail
- Communication
- Organisation
- Initiative
Internal Key Relationships
- Head of Laboratory Operations
- Health&Safety Officer
- Research Group Leaders
- Advanced technology Heads
- IT
- HR
External Key Relationships
- Company service engineers
- Company sales reps.
Languages
ENGLISH
Level: Good
Benefits
- Competitive salary and benefits package.
- Opportunity for professional development and growth within a cutting-edge research environment.
Eligibility criteria / How to apply
All CVs and motivation letters will be reviewed by the selection committee. Reference letters will be requested from shortlisted candidates, and those candidates deemed particularly well suited for the position will be invited for an interview.
Candidates must provide a single PDF file named "NameSurname_LT2_AOP_BCPCC" to "[email protected]" containing:
1. A letter of motivation (max. 2 pages) highlighting your suitability for the role, salary expectations and notice period;
2. CV (max. 2 pages);
3. Names and contact of at least 2 references. If you do not wish that we contact current or past employers, please state so and explain why in your letter of motivation.
Selection process
All CVs and motivation letters will be reviewed by the selection committee. Reference letters will be requested from shortlisted candidates, and those candidates deemed particularly well suited for the position will be invited for an interview.
SELECTION COMMITTEE
Craig Nourse (Manager Advanced Omics Platforms)
Inês Sousa (Senior Research Technician)
Peter Bailey (Director of Translational Research)
About Us
The Botton-Champalimaud Pancreatic Cancer Centre is a state-of-the-art facility comprising research laboratories, a day hospital, a surgical centre, as well as inpatient and intensive care facilities. The mission of the Botton-Champalimaud Pancreatic Cancer Centre is to develop new and effective treatments for pancreatic cancer. To accomplish this goal a multidisciplinary team of surgeons, clinicians, clinical trials specialists, cancer scientists, genomics experts and computational biologists work together to deliver world-leading outcomes for patients with pancreatic cancer.
The Botton-Champalimaud Pancreatic Cancer Centre is also closely integrated with the Champalimaud Centre for the Unknown. Members of the Champalimaud Research Programme (CR) and the Champalimaud Clinical Centre (CCC), work together to investigate fundamental biological processes and search for effective solutions to alleviate the burden of oncological, neurological and mental diseases, while providing state-of-the-art care to the patients of the CCC. With 479 members, including group leaders, postdocs, PhD and MSc students, research technicians and highly specialised research staff, the CR community encompasses 39 nationalities.
Within the Lisbon Ocean Campus, CF will expand its research, technological development, innovation, and clinical practice in the digital therapeutics field.
Additional Institutional Information
In line with our community guidelines and Equality, Diversity and Inclusion policy and Gender Equality Plan, no candidate may be privileged, favoured, prejudiced or deprived of any right or excluded from any duty on the basis of age, sex, gender identity, sexual orientation, race/ethnicity, disability, chronic illness, language, nationality, territory of origin, family status (marital, pregnancy and maternity, having or not having dependents), socioeconomic situation, education, religion, political or ideological beliefs, trade union membership, or on any other grounds which are irrelevant to decision-making.
Legal Notices
The present call has the sole purpose of filling the indicated research position. This call may be cancelled at any time on or before the jury’s evaluation of all eligible candidates and the recruitment process shall be concluded on the day of the full execution of the contract between the Champalimaud Foundation and the selected candidate.
